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Complete Dissociation of Motor Neuron Death from Motor Dysfunction by Bax Deletion in a Mouse Model of ALS
The death of cranial and spinal motoneurons (MNs) is believed to be an essential component of the pathogenesis of amyotrophic lateral sclerosis (ALS). We tested this hypothesis by crossing Bax-deficient mice with mice expressing mutant superoxide dismutase 1 (SOD1), a transgenic model of familial AL...
Gespeichert in:
| Veröffentlicht in: | J Neurosci |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Society for Neuroscience
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6674380/ https://ncbi.nlm.nih.gov/pubmed/16928866 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2315-06.2006 |
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