Programmed Cell Death of Adult-Generated Hippocampal Neurons Is Mediated by the Proapoptotic Gene Bax

In the dentate gyrus (DG) of the adult mouse hippocampus, a substantial number of new cells are generated daily, but only a subset of these survive and differentiate into mature neurons, whereas the majority undergo programmed cell death (PCD). However, neither the intracellular machinery required f...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Sun, Woong, Winseck, Adam, Vinsant, Sharon, Park, Ok-hee, Kim, Hyun, Oppenheim, Ronald W.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2004
Assuntos:
Development/Plasticity/Repair
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6730275/
https://ncbi.nlm.nih.gov/pubmed/15590937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1436-04.2004
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