Human Tobacco Smokers in Early Abstinence Have Higher Levels of β(2)* Nicotinic Acetylcholine Receptors than Nonsmokers

Nicotine, the addictive chemical in tobacco smoke, initiates its actions in brain through nicotinic acetylcholine receptors (nAChRs). In particular, nAChRs containing β(2)-subunits (β(2)*-nAChRs) the most prevalent subtype, mediate the reinforcing properties of nicotine. We hypothesized that abnorma...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Staley, Julie K., Krishnan-Sarin, Suchitra, Cosgrove, Kelly P., Krantzler, Erica, Frohlich, Erin, Perry, Edward, Dubin, Joel A., Estok, Kristina, Brenner, Eric, Baldwin, Ronald M., Tamagnan, Gilles D., Seibyl, John P., Jatlow, Peter, Picciotto, Marina R., London, Edythe D., O'Malley, Stephanie, van Dyck, Christopher H.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2006
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674379/
https://ncbi.nlm.nih.gov/pubmed/16928859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0546-06.2006
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