Human Tobacco Smokers in Early Abstinence Have Higher Levels of β(2)* Nicotinic Acetylcholine Receptors than Nonsmokers

Nicotine, the addictive chemical in tobacco smoke, initiates its actions in brain through nicotinic acetylcholine receptors (nAChRs). In particular, nAChRs containing β(2)-subunits (β(2)*-nAChRs) the most prevalent subtype, mediate the reinforcing properties of nicotine. We hypothesized that abnorma...

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發表在:J Neurosci
Main Authors: Staley, Julie K., Krishnan-Sarin, Suchitra, Cosgrove, Kelly P., Krantzler, Erica, Frohlich, Erin, Perry, Edward, Dubin, Joel A., Estok, Kristina, Brenner, Eric, Baldwin, Ronald M., Tamagnan, Gilles D., Seibyl, John P., Jatlow, Peter, Picciotto, Marina R., London, Edythe D., O'Malley, Stephanie, van Dyck, Christopher H.
格式: Artigo
語言:Inglês
出版: Society for Neuroscience 2006
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Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674379/
https://ncbi.nlm.nih.gov/pubmed/16928859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0546-06.2006
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