Human Tobacco Smokers in Early Abstinence Have Higher Levels of β(2)* Nicotinic Acetylcholine Receptors than Nonsmokers

Nicotine, the addictive chemical in tobacco smoke, initiates its actions in brain through nicotinic acetylcholine receptors (nAChRs). In particular, nAChRs containing β(2)-subunits (β(2)*-nAChRs) the most prevalent subtype, mediate the reinforcing properties of nicotine. We hypothesized that abnorma...

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Vydáno v:J Neurosci
Hlavní autoři: Staley, Julie K., Krishnan-Sarin, Suchitra, Cosgrove, Kelly P., Krantzler, Erica, Frohlich, Erin, Perry, Edward, Dubin, Joel A., Estok, Kristina, Brenner, Eric, Baldwin, Ronald M., Tamagnan, Gilles D., Seibyl, John P., Jatlow, Peter, Picciotto, Marina R., London, Edythe D., O'Malley, Stephanie, van Dyck, Christopher H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2006
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674379/
https://ncbi.nlm.nih.gov/pubmed/16928859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0546-06.2006
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