The Chk1/Cdc25A Pathway as Activators of the Cell Cycle in Neuronal Death Induced by Camptothecin

Cell cycle regulators appear to play a paradoxical role in neuronal death. We have shown previously that cyclin-dependent kinases (CDKs), along with their downstream effectors, Rb (retinoblastoma) and E2F/DP1 (E2 promoter binding factor/deleted in polyposis 1), regulate neuronal death evoked by the...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Zhang, Yi, Qu, Dianbo, Morris, Erick J., O’Hare, Michael J., Callaghan, Steven M., Slack, Ruth S., Geller, Herbert M., Park, David S.
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2006
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674376/
https://ncbi.nlm.nih.gov/pubmed/16928871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2593-06.2006
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