Learning and Memory and Synaptic Plasticity Are Impaired in a Mouse Model of Rett Syndrome

Loss-of-function mutations or abnormal expression of the X-linked gene encoding methyl CpG binding protein 2 (MeCP2) cause a spectrum of postnatal neurodevelopmental disorders including Rett syndrome (RTT), nonsyndromic mental retardation, learning disability, and autism. Mice expressing a truncated...

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Dades bibliogràfiques
Publicat a:J Neurosci
Autors principals: Moretti, Paolo, Levenson, Jonathan M., Battaglia, Fortunato, Atkinson, Richard, Teague, Ryan, Antalffy, Barbara, Armstrong, Dawna, Arancio, Ottavio, Sweatt, J. David, Zoghbi, Huda Y.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2006
Matèries:
Neurobiology of Disease
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674314/
https://ncbi.nlm.nih.gov/pubmed/16399702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2623-05.2006
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