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Endogenous α-Synuclein Is Induced by Valproic Acid through Histone Deacetylase Inhibition and Participates in Neuroprotection against Glutamate-Induced Excitotoxicity

Emerging evidence suggests that α-synuclein (α-syn), which is traditionally thought to have a pathophysiological role in neurodegenerative diseases, can have neuroprotective effects. This study aimed to investigate whether endogenous α-syn in neurons can be induced by valproic acid (VPA), a mood-sta...

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Bibliographische Detailangaben
Veröffentlicht in:J Neurosci
Hauptverfasser: Leng, Yan, Chuang, De-Maw
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674182/
https://ncbi.nlm.nih.gov/pubmed/16837598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0096-06.2006
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