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Neuroprotective effects of the mood stabilizer lamotrigine against glutamate excitotoxicity: roles of chromatin remodelling and Bcl-2 induction

Lamotrigine (LTG), a phenyltriazine derivative and anti-epileptic drug, has emerged as an effective first-line treatment for bipolar mood disorder. Like the other mood stabilizers lithium and valproate, LTG also has neuroprotective properties but its exact mechanisms remain poorly defined. The prese...

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Detalhes bibliográficos
Publicado no:Int J Neuropsychopharmacol
Main Authors: Leng, Yan, Fessler, Emily Bame, Chuang, De-Maw
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6324934/
https://ncbi.nlm.nih.gov/pubmed/22564541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/S1461145712000429
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