System X(c)(−) and Apolipoprotein E Expressed by Microglia Have Opposite Effects on the Neurotoxicity of Amyloid-β Peptide 1–40

Because senile plaques in Alzheimer's disease (AD) contain reactive microglia in addition to potentially neurotoxic aggregates of amyloid-β (Aβ), we examined the influence of microglia on the viability of rodent neurons in culture exposed to aggregated Aβ 1–40. Microglia enhanced the toxicity o...

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Vydáno v:J Neurosci
Hlavní autoři: Qin, Si, Colin, Catherine, Hinners, Ina, Gervais, Annie, Cheret, Cyril, Mallat, Michel
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2006
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674113/
https://ncbi.nlm.nih.gov/pubmed/16554485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5186-05.2006
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