Neurotoxic Activation of Microglia Is Promoted by a Nox1-Dependent NADPH Oxidase

Reactive oxygen species (ROS) modulate intracellular signaling but are also responsible for neuronal damage in pathological states. Microglia, the resident CNS macrophages, are prominent sources of ROS through expression of the phagocyte oxidase which catalytic subunit Nox2 generates superoxide ion...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Chéret, Cyril, Gervais, Annie, Lelli, Aurélia, Colin, Catherine, Amar, Lahouari, Ravassard, Philippe, Mallet, Jacques, Cumano, Ana, Krause, Karl-Heinz, Mallat, Michel
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2008
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6671643/
https://ncbi.nlm.nih.gov/pubmed/19005069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3568-08.2008
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