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Tau Protects Microtubules in the Axon from Severing by Katanin

Microtubules in the axon are more resistant to severing by katanin than microtubules elsewhere in the neuron. We have hypothesized that this is because of the presence of tau on axonal microtubules. When katanin is overexpressed in fibroblasts, the microtubules are severed into short pieces, but thi...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Qiang, Liang, Yu, Wenqian, Andreadis, Athena, Luo, Minhua, Baas, Peter W.
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674103/
https://ncbi.nlm.nih.gov/pubmed/16554463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5392-05.2006
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