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Tau Protects Microtubules in the Axon from Severing by Katanin

Microtubules in the axon are more resistant to severing by katanin than microtubules elsewhere in the neuron. We have hypothesized that this is because of the presence of tau on axonal microtubules. When katanin is overexpressed in fibroblasts, the microtubules are severed into short pieces, but thi...

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Detalles Bibliográficos
Publicado en:J Neurosci
Main Authors: Qiang, Liang, Yu, Wenqian, Andreadis, Athena, Luo, Minhua, Baas, Peter W.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674103/
https://ncbi.nlm.nih.gov/pubmed/16554463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5392-05.2006
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