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Tau Protects Microtubules in the Axon from Severing by Katanin

Microtubules in the axon are more resistant to severing by katanin than microtubules elsewhere in the neuron. We have hypothesized that this is because of the presence of tau on axonal microtubules. When katanin is overexpressed in fibroblasts, the microtubules are severed into short pieces, but thi...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Qiang, Liang, Yu, Wenqian, Andreadis, Athena, Luo, Minhua, Baas, Peter W.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674103/
https://ncbi.nlm.nih.gov/pubmed/16554463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5392-05.2006
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