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Tau Protects Microtubules in the Axon from Severing by Katanin

Microtubules in the axon are more resistant to severing by katanin than microtubules elsewhere in the neuron. We have hypothesized that this is because of the presence of tau on axonal microtubules. When katanin is overexpressed in fibroblasts, the microtubules are severed into short pieces, but thi...

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Foilsithe in:J Neurosci
Main Authors: Qiang, Liang, Yu, Wenqian, Andreadis, Athena, Luo, Minhua, Baas, Peter W.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Society for Neuroscience 2006
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674103/
https://ncbi.nlm.nih.gov/pubmed/16554463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5392-05.2006
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