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State-Dependent Cross-Linking of the M2 and M3 Segments: Functional Basis for the Alignment of GABA(A) and Acetylcholine Receptor M3 Segments

Construction of a GABA(A) receptor homology model based on the acetylcholine (ACh) receptor structure is complicated by the low sequence similarity between GABA(A) and ACh M3 transmembrane segments that creates significant uncertainty in their alignment. We determined the orientation of the GABA(A)...

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Pubblicato in:J Neurosci
Autori principali: Jansen, Michaela, Akabas, Myles H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674078/
https://ncbi.nlm.nih.gov/pubmed/16641228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0224-06.2006
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