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Presynaptic α-Synuclein Aggregates, Not Lewy Bodies, Cause Neurodegeneration in Dementia with Lewy Bodies
Lewy bodies, the pathological hallmark of dementia with Lewy bodies (DLB), are large juxtanuclear inclusions of aggregated α-synuclein. However, the small number of cortical Lewy bodies relative to the total neuron count does not correlate with the extent of cognitive impairment. In contrast to dopa...
Shranjeno v:
| izdano v: | J Neurosci |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Society for Neuroscience
2007
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6673583/ https://ncbi.nlm.nih.gov/pubmed/17287515 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4564-06.2007 |
| Oznake: |
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