Chronic Interleukin-1β Expression in Mouse Brain Leads to Leukocyte Infiltration and Neutrophil-Independent Blood–Brain Barrier Permeability without Overt Neurodegeneration

The proinflammatory cytokine interleukin-1β (IL-1β) plays a significant role in leukocyte recruitment to the CNS. Although acute effects of IL-1β signaling in the mouse brain have been well described, studies elucidating the downstream effects of sustained upregulation have been lacking. Using the r...

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Bibliografiska uppgifter
I publikationen:J Neurosci
Huvudupphovsmän: Shaftel, Solomon S., Carlson, Thaddeus J., Olschowka, John A., Kyrkanides, Stephanos, Matousek, Sarah B., O'Banion, M. Kerry
Materialtyp: Artigo
Språk:Inglês
Publicerad: Society for Neuroscience 2007
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673122/
https://ncbi.nlm.nih.gov/pubmed/17728444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1418-07.2007
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