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Peripheral blood mononuclear cell infiltration and neuroinflammation in the HexB(−/−) mouse model of neurodegeneration

Myeloid-derived immune cells, including microglia, macrophages and monocytes, have been previously implicated in neurodegeneration. We investigated the role of infiltrating peripheral blood mononuclear cells (PBMC) in neuroinflammation and neurodegeneration in the HexB(−/−) mouse model of Sandhoff d...

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Detalhes bibliográficos
Main Authors: Kyrkanides, Stephanos, Miller, Ann W., Miller, Jen-nie H., Tallents, Ross H., Brouxhon, Sabine M., Olschowka, Malory E., O’Banion, M. Kerry, Olschowka, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612729/
https://ncbi.nlm.nih.gov/pubmed/18657867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2008.06.024
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