Repair Capacity for Platinum-DNA Adducts Determines the Severity of Cisplatin-Induced Peripheral Neuropathy

The pronounced neurotoxicity of the potent antitumor drug cisplatin frequently results in the onset of peripheral polyneuropathy (PNP), which is assumed to be initially triggered by platination products in the nuclear DNA of affected tissues. To further elucidate the molecular mechanisms, we analyze...

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Xehetasun bibliografikoak
Argitaratua izan da:J Neurosci
Egile Nagusiak: Dzagnidze, Anna, Katsarava, Zaza, Makhalova, Julia, Liedert, Bernd, Yoon, Min-Suk, Kaube, Holger, Limmroth, Volker, Thomale, Juergen
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Society for Neuroscience 2007
Gaiak:
Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673116/
https://ncbi.nlm.nih.gov/pubmed/17728458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0523-07.2007
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