Erythropoietin overrides the triggering effect of DNA platination products in a mouse model of Cisplatin-induced neuropathy

BACKGROUND: Cisplatin mediates its antineoplastic activity by formation of distinct DNA intrastrand cross links. The clinical efficacy and desirable dose escalations of cisplatin are restricted by the accumulation of DNA lesions in dorsal root ganglion (DRG) cells leading to sensory polyneuropathy (...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Yoon, Min-Suk, Katsarava, Zaza, Obermann, Mark, Schäfers, Maria, Liedert, Bernd, Dzagnidze, Anna, Kribben, Andreas, Egensperger, Rupert, Limmroth, Volker, Diener, Hans-Christoph, Thomale, Juergen
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2009
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2716353/
https://ncbi.nlm.nih.gov/pubmed/19602296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-10-77
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares