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Nonpsychoactive Cannabidiol Prevents Prion Accumulation and Protects Neurons against Prion Toxicity

Prion diseases are transmissible neurodegenerative disorders characterized by the accumulation in the CNS of the protease-resistant prion protein (PrPres), a structurally misfolded isoform of its physiological counterpart PrPsen. Both neuropathogenesis and prion infectivity are related to PrPres for...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Dirikoc, Sevda, Priola, Suzette A., Marella, Mathieu, Zsürger, Nicole, Chabry, Joëlle
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672971/
https://ncbi.nlm.nih.gov/pubmed/17804615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1942-07.2007
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