Upregulation of Acid-Sensing Ion Channel ASIC1a in Spinal Dorsal Horn Neurons Contributes to Inflammatory Pain Hypersensitivity

Development of chronic pain involves alterations in peripheral nociceptors as well as elevated neuronal activity in multiple regions of the CNS. Previous pharmacological and behavioral studies suggest that peripheral acid-sensing ion channels (ASICs) contribute to pain sensation, and the expression...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Duan, Bo, Wu, Long-Jun, Yu, Yao-Qing, Ding, Yu, Jing, Liang, Xu, Lin, Chen, Jun, Xu, Tian-Le
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672839/
https://ncbi.nlm.nih.gov/pubmed/17928456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3364-07.2007
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