Brain-Derived Neurotrophic Factor Expression and Respiratory Function Improve after Ampakine Treatment in a Mouse Model of Rett Syndrome

Rett syndrome (RTT) is caused by loss-of-function mutations in the gene encoding methyl-CpG-binding protein 2 (MeCP2). Although MeCP2 is thought to act as a transcriptional repressor of brain-derived neurotrophic factor (BDNF), Mecp2 null mice, which develop an RTT-like phenotype, exhibit progressiv...

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Vydáno v:J Neurosci
Hlavní autoři: Ogier, Michael, Wang, Hong, Hong, Elizabeth, Wang, Qifang, Greenberg, Michael E., Katz, David M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2007
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672830/
https://ncbi.nlm.nih.gov/pubmed/17913925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1869-07.2007
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