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Dysregulation of Brain-Derived Neurotrophic Factor Expression and Neurosecretory Function in Mecp2 Null Mice

Disruptions in brain-derived neurotrophic factor (BDNF) expression are proposed to contribute to the molecular pathogenesis of Rett syndrome (RTT), a severe neurological disorder caused by loss-of-function mutations in methyl-CpG-binding protein-2 (MeCP2). Although MeCP2 is a transcriptional regulat...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Wang, Hong, Chan, Shyue-an, Ogier, Michael, Hellard, David, Wang, Qifang, Smith, Corey, Katz, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674736/
https://ncbi.nlm.nih.gov/pubmed/17050729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1810-06.2006
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