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Remodelling of the respiratory network in a mouse model of Rett syndrome depends on brain-derived neurotrophic factor regulated slow calcium buffering

Rett syndrome caused by MeCP2 mutations is a devastating neurodevelopmental disorder accompanied by severe breathing irregularities. Using transduction of organotypic slices from model MeCP2–/y mice with neuron-specific calcium sensor protein D3cpv, we examined the slow calcium buffering in neurons...

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Detalhes bibliográficos
Main Authors: Mironov, S L, Skorova, E, Hartelt, N, Mironova, L A, Hasan, M T, Kügler, S
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2714014/
https://ncbi.nlm.nih.gov/pubmed/19359374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.169805
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