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Demyelination, Astrogliosis, and Accumulation of Ubiquitinated Proteins, Hallmarks of CNS Disease in hsf1-Deficient Mice

The heat shock transcription factors (Hsfs) are responsible for the heat shock response, an evolutionarily conserved process for clearance of damaged and aggregated proteins. In organisms such as Caenorhabditis elegans, which contain a single Hsf, reduction in the level of Hsf is associated with the...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Homma, Sachiko, Jin, Xiongjie, Wang, Guanghu, Tu, Naxin, Min, Jinna, Yanasak, Nathan, Mivechi, Nahid F.
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2007
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672719/
https://ncbi.nlm.nih.gov/pubmed/17652588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0006-07.2007
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