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The transcriptional regulator of the chaperone response HSF1 controls hepatic bioenergetics and protein homeostasis
Metabolic energy reprogramming facilitates adaptations to a variety of stress conditions and cellular dysfunction, but how the energetic demands are monitored and met in response to physiological stimuli remains elusive. Our data support a model demonstrating that heat shock factor 1 (HSF1), a maste...
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Publicado no: | J Cell Biol |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Rockefeller University Press
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5350514/ https://ncbi.nlm.nih.gov/pubmed/28183717 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201607091 |
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