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The transcriptional regulator of the chaperone response HSF1 controls hepatic bioenergetics and protein homeostasis

Metabolic energy reprogramming facilitates adaptations to a variety of stress conditions and cellular dysfunction, but how the energetic demands are monitored and met in response to physiological stimuli remains elusive. Our data support a model demonstrating that heat shock factor 1 (HSF1), a maste...

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Vydáno v:J Cell Biol
Hlavní autoři: Qiao, Aijun, Jin, Xiongjie, Pang, Junfeng, Moskophidis, Demetrius, Mivechi, Nahid F.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5350514/
https://ncbi.nlm.nih.gov/pubmed/28183717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201607091
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