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Heat shock transcription factor 1 is a key determinant of HCC development by regulating hepatic steatosis and metabolic syndrome
Hepatocellular carcinoma (HCC) occurrence and progression is linked tightly to progressive hepatic metabolic syndrome associated with insulin resistance, hepatic steatosis, and chronic inflammation. Heat shock transcription factor 1 (HSF1), a major transactivator of stress proteins, increases surviv...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3214631/ https://ncbi.nlm.nih.gov/pubmed/21723507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2011.03.025 |
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