M(1) and M(3) Muscarinic Receptors Control Physiological Processing of Cellular Prion by Modulating ADAM17 Phosphorylation and Activity

The cellular prion protein (PrP(c)) undergoes a physiological processing yielding the N-terminal fragment referred to as N1, the production of which can be constitutive or protein kinase C regulated. We show that activation of endogenous muscarinic receptors by carbachol and by the M(1)-selective ag...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Alfa Cissé, Moustapha, Sunyach, Claire, Slack, Barbara E., Fisher, Abraham, Vincent, Bruno, Checler, Frédéric
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2007
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672535/
https://ncbi.nlm.nih.gov/pubmed/17428986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5293-06.2007
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