Dysregulated Metabotropic Glutamate Receptor-Dependent Translation of AMPA Receptor and Postsynaptic Density-95 mRNAs at Synapses in a Mouse Model of Fragile X Syndrome

Fragile X syndrome, a common form of inherited mental retardation, is caused by the loss of fragile X mental retardation protein (FMRP), an mRNA binding protein that is hypothesized to regulate local mRNA translation in dendrites downstream of gp1 metabotropic glutamate receptors (mGluRs). However,...

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Vydáno v:J Neurosci
Hlavní autoři: Muddashetty, Ravi S., Kelić, Sofija, Gross, Christina, Xu, Mei, Bassell, Gary J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2007
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672337/
https://ncbi.nlm.nih.gov/pubmed/17507556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0937-07.2007
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