Widespread Disruption of Repressor Element-1 Silencing Transcription Factor/Neuron-Restrictive Silencer Factor Occupancy at Its Target Genes in Huntington's Disease

Huntingtin is a protein that is mutated in Huntington's disease (HD), a dominant inherited neurodegenerative disorder. We previously proposed that, in addition to the gained toxic activity of the mutant protein, selective molecular dysfunctions in HD may represent the consequences of the loss o...

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Foilsithe in:J Neurosci
Main Authors: Zuccato, Chiara, Belyaev, Nikolai, Conforti, Paola, Ooi, Lezanne, Tartari, Marzia, Papadimou, Evangelia, MacDonald, Marcy, Fossale, Elisa, Zeitlin, Scott, Buckley, Noel, Cattaneo, Elena
Formáid: Artigo
Teanga:Inglês
Foilsithe: Society for Neuroscience 2007
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Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672230/
https://ncbi.nlm.nih.gov/pubmed/17596446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4278-06.2007
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