Widespread Disruption of Repressor Element-1 Silencing Transcription Factor/Neuron-Restrictive Silencer Factor Occupancy at Its Target Genes in Huntington's Disease

Huntingtin is a protein that is mutated in Huntington's disease (HD), a dominant inherited neurodegenerative disorder. We previously proposed that, in addition to the gained toxic activity of the mutant protein, selective molecular dysfunctions in HD may represent the consequences of the loss o...

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Publicado en:J Neurosci
Main Authors: Zuccato, Chiara, Belyaev, Nikolai, Conforti, Paola, Ooi, Lezanne, Tartari, Marzia, Papadimou, Evangelia, MacDonald, Marcy, Fossale, Elisa, Zeitlin, Scott, Buckley, Noel, Cattaneo, Elena
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2007
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672230/
https://ncbi.nlm.nih.gov/pubmed/17596446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4278-06.2007
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