Widespread Disruption of Repressor Element-1 Silencing Transcription Factor/Neuron-Restrictive Silencer Factor Occupancy at Its Target Genes in Huntington's Disease

Huntingtin is a protein that is mutated in Huntington's disease (HD), a dominant inherited neurodegenerative disorder. We previously proposed that, in addition to the gained toxic activity of the mutant protein, selective molecular dysfunctions in HD may represent the consequences of the loss o...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Zuccato, Chiara, Belyaev, Nikolai, Conforti, Paola, Ooi, Lezanne, Tartari, Marzia, Papadimou, Evangelia, MacDonald, Marcy, Fossale, Elisa, Zeitlin, Scott, Buckley, Noel, Cattaneo, Elena
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672230/
https://ncbi.nlm.nih.gov/pubmed/17596446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4278-06.2007
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