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Different Species of α-Synuclein Oligomers Induce Calcium Influx and Seeding

Aggregation of α-synuclein (α-syn) has been linked to the pathogenesis of Parkinson's disease (PD) and other neurodegenerative diseases. Increasing evidence suggests that prefibrillar oligomers and protofibrils, rather than mature fibrils of α-syn, are the pathogenic species in PD. Despite exte...

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Pubblicato in:J Neurosci
Autori principali: Danzer, Karin M., Haasen, Dorothea, Karow, Anne R., Moussaud, Simon, Habeck, Matthias, Giese, Armin, Kretzschmar, Hans, Hengerer, Bastian, Kostka, Marcus
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672196/
https://ncbi.nlm.nih.gov/pubmed/17715357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2617-07.2007
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