Deletion of Apolipoprotein E Receptor-2 in Mice Lowers Brain Selenium and Causes Severe Neurological Dysfunction and Death When a Low-Selenium Diet Is Fed

Selenoprotein P (Sepp1) is a plasma and extracellular protein that is rich in selenium. Deletion of Sepp1 results in sharp decreases of selenium levels in the brain and testis with dysfunction of those organs. Deletion of Sepp1 also causes increased urinary selenium excretion, leading to moderate de...

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Опубликовано в: :J Neurosci
Главные авторы: Burk, Raymond F., Hill, Kristina E., Olson, Gary E., Weeber, Edwin J., Motley, Amy K., Winfrey, Virginia P., Austin, Lori M.
Формат: Artigo
Язык:Inglês
Опубликовано: Society for Neuroscience 2007
Предметы:
Brief Communications
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672153/
https://ncbi.nlm.nih.gov/pubmed/17553992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1153-07.2007
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