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Deletion of Selenoprotein P Upregulates Urinary Selenium Excretion and Depresses Whole-body Selenium Content
Deletion of the mouse selenoprotein P gene (Sepp1) lowers selenium concentrations in many tissues. We examined selenium homeostasis in Sepp1(−/−) and Sepp1(+/+) mice to assess the mechanism of this. The liver produces and exports selenoprotein P, which transports selenium to peripheral tissues, and...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1761947/ https://ncbi.nlm.nih.gov/pubmed/17014962 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2006.08.010 |
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