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Production of Selenoprotein P (Sepp1) by Hepatocytes Is Central to Selenium Homeostasis
Sepp1 is a widely expressed extracellular protein that in humans and mice contains 10 selenocysteine residues in its primary structure. Extra-hepatic tissues take up plasma Sepp1 for its selenium via apolipoprotein E receptor-2 (apoER2)-mediated endocytosis. The role of Sepp1 in the transport of sel...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3504756/ https://ncbi.nlm.nih.gov/pubmed/23038251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.421404 |
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