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Lack of Hypoxia-Inducible Factor-1α Impairs Midbrain Neural Precursor Cells Involving Vascular Endothelial Growth Factor Signaling
Oxygen tension is critical for proliferation of human and murine midbrain-derived neural precursor cells (mNPCs). Here, we conditionally inactivated the hypoxia-responsive transcription factor hypoxia-inducible factor-1α (HIF-1α) in murine NPCs to determine its role in proliferation, survival, and d...
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| Pubblicato in: | J Neurosci |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Society for Neuroscience
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6672078/ https://ncbi.nlm.nih.gov/pubmed/17215402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2482-06.2007 |
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