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Deriving Mechanisms Responsible for the Lack of Correlation between Hypoxia and Acidity in Solid Tumors

Hypoxia and acidity are two main microenvironmental factors intimately associated with solid tumors and play critical roles in tumor growth and metastasis. The experimental results of Helmlinger and colleagues (Nature Medicine 3, 177, 1997) provide evidence of a lack of correlation between these fac...

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Autors principals: Molavian, Hamid R., Kohandel, Mohammad, Milosevic, Michael, Sivaloganathan, Sivabal
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3235095/
https://ncbi.nlm.nih.gov/pubmed/22174768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028101
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