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Deriving Mechanisms Responsible for the Lack of Correlation between Hypoxia and Acidity in Solid Tumors

Hypoxia and acidity are two main microenvironmental factors intimately associated with solid tumors and play critical roles in tumor growth and metastasis. The experimental results of Helmlinger and colleagues (Nature Medicine 3, 177, 1997) provide evidence of a lack of correlation between these fac...

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Detalhes bibliográficos
Main Authors: Molavian, Hamid R., Kohandel, Mohammad, Milosevic, Michael, Sivaloganathan, Sivabal
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3235095/
https://ncbi.nlm.nih.gov/pubmed/22174768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028101
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