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ApoC-III ASO promotes tissue LPL activity in the absence of apoE-mediated TRL clearance
Hypertriglyceridemia results from accumulation of triglyceride (TG)-rich lipoproteins (TRLs) in the circulation and is associated with increased CVD risk. ApoC-III is an apolipoprotein on TRLs and a prominent negative regulator of TG catabolism. We recently established that in vivo apoC-III predomin...
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| Gepubliceerd in: | J Lipid Res |
|---|---|
| Hoofdauteurs: | , , , , , , , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
The American Society for Biochemistry and Molecular Biology
2019
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6672034/ https://ncbi.nlm.nih.gov/pubmed/31092690 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M093740 |
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