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ApoC-III Glycoforms Are Differentially Cleared by Hepatic Triglyceride-Rich Lipoprotein Receptors

OBJECTIVE: ApoC-III glycosylation can predict cardiovascular disease risk. Higher abundance of disialylated (apoC-III(2)) over monosialylated (apoC-III(1)) glycoforms is associated with lower plasma triglyceride levels. Yet, it remains unclear whether apoC-III glycosylation impacts TRL clearance and...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Kegulian, Natalie C., Ramms, Bastian, Horton, Steven, Trenchevska, Olgica, Nedelkov, Dobrin, Graham, Mark J., Lee, Richard G., Esko, Jeffrey D., Yassine, Hussein N., Gordts, Philip L.S.M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6761044/
https://ncbi.nlm.nih.gov/pubmed/31390883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.119.312723
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