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Regioisomer-independent quantification of fatty acid oxidation products by HPLC-ESI-MS/MS analysis of sodium adducts

Despite growing acknowledgement of the role of oxidized fatty acids (oxFA) as cellular signaling molecules and in the pathogenesis of disease, developing methods to measure these species in biological samples has proven challenging. Here we describe a novel method utilizing HPLC-ESI-MS/MS to identif...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ahern, Katelyn W., Serbulea, Vlad, Wingrove, Catherine L., Palas, Zachary T., Leitinger, Norbert, Harris, Thurl E.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6671977/
https://ncbi.nlm.nih.gov/pubmed/31371760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47693-5
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