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Regioisomer-independent quantification of fatty acid oxidation products by HPLC-ESI-MS/MS analysis of sodium adducts

Despite growing acknowledgement of the role of oxidized fatty acids (oxFA) as cellular signaling molecules and in the pathogenesis of disease, developing methods to measure these species in biological samples has proven challenging. Here we describe a novel method utilizing HPLC-ESI-MS/MS to identif...

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Vydáno v:Sci Rep
Hlavní autoři: Ahern, Katelyn W., Serbulea, Vlad, Wingrove, Catherine L., Palas, Zachary T., Leitinger, Norbert, Harris, Thurl E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6671977/
https://ncbi.nlm.nih.gov/pubmed/31371760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47693-5
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