Amyloid Pathology Is Associated with Progressive Monoaminergic Neurodegeneration in a Transgenic Mouse Model of Alzheimer's Disease

β-Amyloid (Aβ) pathology is an essential pathogenic component in Alzheimer's disease (AD). However, the significance of Aβ pathology, including Aβ deposits/oligomers and glial reactions, to neurodegeneration is unclear. In particular, despite the Aβ neurotoxicity indicated by in vitro studies,...

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Gepubliceerd in:J Neurosci
Hoofdauteurs: Liu, Ying, Yoo, Mi-Jeong, Savonenko, Alena, Stirling, Wanda, Price, Donald L., Borchelt, David R., Mamounas, Laura, Lyons, W. Ernest, Blue, Mary E., Lee, Michael K.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society for Neuroscience 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6671923/
https://ncbi.nlm.nih.gov/pubmed/19091971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4218-08.2008
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