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Mutant and wild-type p53 complex with p73 in response to JNK phosphorylation
Mutant p53 and p73 have been shown to form a complex, which renders p73 inactive, but it has been previously reported that wild-type p53 does not interact with p73. Mutations in the DNA binding domain of p53 result in structural changes that are permissive for interaction with p73. In a mouse model,...
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| Izdano u: | Sci Signal |
|---|---|
| Glavni autori: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2018
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6671681/ https://ncbi.nlm.nih.gov/pubmed/29615516 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aao4170 |
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