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Mutant and wild-type p53 complex with p73 in response to JNK phosphorylation

Mutant p53 and p73 have been shown to form a complex, which renders p73 inactive, but it has been previously reported that wild-type p53 does not interact with p73. Mutations in the DNA binding domain of p53 result in structural changes that are permissive for interaction with p73. In a mouse model,...

詳細記述

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書誌詳細
出版年:Sci Signal
主要な著者: Wolf, Eric R., McAtarsney, Ciaran P., Bredhold, Kristin E., Kline, Amber M., Mayo, Lindsey D.
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6671681/
https://ncbi.nlm.nih.gov/pubmed/29615516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aao4170
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