Cysteine-Rich Protein 2, a Novel Downstream Effector of cGMP/cGMP-Dependent Protein Kinase I-Mediated Persistent Inflammatory Pain

The cGMP/cGMP-dependent protein kinase I (cGKI) signaling pathway plays an important role in spinal nociceptive processing. However, downstream targets of cGKI in this context have not been identified to date. Using a yeast two-hybrid screen, we isolated cysteine-rich protein 2 (CRP2) as a novel cGK...

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Pubblicato in:J Neurosci
Autori principali: Schmidtko, Achim, Gao, Wei, Sausbier, Matthias, Rauhmeier, Inga, Sausbier, Ulrike, Niederberger, Ellen, Scholich, Klaus, Huber, Andrea, Neuhuber, Winfried, Allescher, Hans-Dieter, Hofmann, Franz, Tegeder, Irmgard, Ruth, Peter, Geisslinger, Gerd
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6671575/
https://ncbi.nlm.nih.gov/pubmed/18256252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5037-07.2008
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