Inflammatory Response in the Hippocampus of PS1(M146L)/APP(751SL) Mouse Model of Alzheimer's Disease: Age-Dependent Switch in the Microglial Phenotype from Alternative to Classic

Although the microglial activation is concomitant to the Alzheimer's disease, its precise role (neuroprotection vs neurodegeneration) has not yet been resolved. Here, we show the existence of an age-dependent phenotypic change of microglial activation in the hippocampus of PS1xAPP model, from a...

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Publicado no:J Neurosci
Main Authors: Jimenez, Sebastian, Baglietto-Vargas, David, Caballero, Cristina, Moreno-Gonzalez, Ines, Torres, Manuel, Sanchez-Varo, Raquel, Ruano, Diego, Vizuete, Marisa, Gutierrez, Antonia, Vitorica, Javier
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2008
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6671312/
https://ncbi.nlm.nih.gov/pubmed/18987201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3024-08.2008
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