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Taurine Is a Potent Activator of Extrasynaptic GABA(A) Receptors in the Thalamus

Taurine is one of the most abundant free amino acids in the brain. In a number of studies, taurine has been reported to activate glycine receptors (Gly-Rs) at moderate concentrations (≥100 μm), and to be a weak agonist at GABA(A) receptors (GABA(A)-Rs), which are usually activated at high concentrat...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Neurosci
Hauptverfasser: Jia, Fan, Yue, Minerva, Chandra, Dev, Keramidas, Angelo, Goldstein, Peter A., Homanics, Gregg E., Harrison, Neil L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6671153/
https://ncbi.nlm.nih.gov/pubmed/18171928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3996-07.2008
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