GABA(A) receptor α4 subunits mediate extrasynaptic inhibition in thalamus and dentate gyrus and the action of gaboxadol

The neurotransmitter GABA mediates the majority of rapid inhibition in the CNS. Inhibition can occur via the conventional mechanism, the transient activation of subsynaptic GABA(A) receptors (GABA(A)-Rs), or via continuous activation of high-affinity receptors by low concentrations of ambient GABA,...

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Autors principals: Chandra, D., Jia, F., Liang, J., Peng, Z., Suryanarayanan, A., Werner, D. F., Spigelman, I., Houser, C. R., Olsen, R. W., Harrison, N. L., Homanics, G. E.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2006
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1578762/
https://ncbi.nlm.nih.gov/pubmed/17005728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604304103
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