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Isoflurane modulates excitability in the mouse thalamus via GABA-dependent and GABA-independent mechanisms

GABAergic neurons in the reticular thalamic nucleus (RTN) synapse onto thalamocortical neurons in the ventrobasal (VB) thalamus, and this reticulo-thalamocortical pathway is considered an anatomic target for general anesthetic-induced unconsciousness. A mutant mouse was engineered to harbor two amin...

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Detalhes bibliográficos
Main Authors: Ying, Shui-Wang, Werner, David F., Homanics, Gregg E., Harrison, Neil L., Goldstein, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668243/
https://ncbi.nlm.nih.gov/pubmed/18948126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2008.09.015
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