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Opposing Patterns of Signaling Activation in Dopamine D(1) and D(2) Receptor-Expressing Striatal Neurons in Response to Cocaine and Haloperidol
Psychostimulants and other drugs of abuse activate extracellular signal-regulated kinase (ERK) in the striatum, through combined stimulation of dopamine D(1) receptors (D1Rs) and glutamate NMDA receptors. Antipsychotic drugs activate similar signaling proteins in the striatum by blocking dopamine D(...
Gespeichert in:
| Veröffentlicht in: | J Neurosci |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Society for Neuroscience
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6670792/ https://ncbi.nlm.nih.gov/pubmed/18509028 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1039-08.2008 |
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